Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ...
Covalent inhibitors are a specialized class of small molecules designed to form chemical bonds with their target proteins, often resulting in prolonged target engagement and enhanced potency. The ...
In a recent study, they demonstrated that a doubly positively charged digallene can activate very strong covalent bonds. The work was highlighted as Pick of the Week in the journal Chemical Science.
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