Authorities say the operation brought more than 300 kilograms of cocaine to Philadelphia from Mexico since 2024.
Mendo Love, 52, was arrested and has been charged with multiple drug-related offenses.
The DEA said agents in Chicago seized 339 lbs. of cocaine and $700,000 in cash from a River Grove, Illinois, bust.
Springfield police arrested five suspects and seized a loaded firearm following a drug investigation.
The drugs, consisting of marijuana and psilocybin products, weighed nearly 10 tons and had a street value of around $50 million, state troopers said.