The anti-CD40 antibody tegoprubart offers a tacrolimus-free immunosuppression option for preventing islet transplant ...

Type 1 diabetes is a disease where the immune system destroys insulin-producing beta cells in pancreatic islets. About 2 million Americans have Type 1 diabetes. The islets of Langerhans are named for ...

When cells copy DNA to produce RNA transcripts, some stretches of the genetic material are included—these are known as exons—but the rest is thrown out. The resulting transcript is a fully mature RNA ...

Daily insulin injections are painful and inconvenient, which is why scientists are developing implants that treat diabetes without any need for needles. A new one looks particularly promising, as it ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. The FDA approved the first allogenic pancreatic islet ...

A vascularized organoid model of hormone-secreting cells in the pancreas has been developed, with potential to improve diabetes research and cell-based therapies. “Our results highlight the importance ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have studied pancreatic islet cell loss in people with no previous pancreatic problems. They identified key trends in the types of cells ...

This article was originally published by CGTLive. It has been lightly edited. Patients with type 1 diabetes (T1D) treated with the stem-cell derived islet cell therapy VX-880 (Vertex Pharmaceuticals) ...

Researchers have devised the right conditions to grow vascularized stem cell islets. The image shows vasculature (red) tightly wrapped around insulin-producing cells (green) in the islets (blue).

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine ...