In a new study, researchers have developed a comprehensive in silico model of the rat hippocampal CA1 region. This model is unique as it integrates a wide range of experimental data, from the synaptic ...

Functional output of the hippocampus, a brain region subserving memory function, depends on highly orchestrated cellular and molecular processes that regulate synaptic plasticity throughout life. The ...

For the first time, a study in rats teases apart the role of the hippocampus in two functions of memory—one that remembers associations between time, place and what one did, and another that allows ...

In a recent study published in Neuronal Psychiatry, researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix ...

Astrocytes can affect animal behavior by regulating tripartite synaptic transmission, yet their influence on affective behavior remains largely unclear. Here we showed that hippocampal astrocyte ...

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles. These hormones not only influence the body, but can cross into the brain and shape the behavior ...

The hippocampus has a surprising new role -- linked to the control of skilled actions such as handwriting, typing, and playing music. Researchers at the University of Birmingham have uncovered a ...

Scientists at USC have unveiled an artificial hippocampus and are planning experiments to determine if it can help replace function in damaged hippocampal tissue. The hippocampus is involved in ...

The hippocampus plays a role in the brain's ability to learn and remember. In the Early Edition of the Proceedings of the National Academy of Sciences, Mody et al. report the use of a microarray ...

Traumatic experiences can cause memory problems, and estrogen may be a key factor that shapes the brain's resilience against ...

In a recent study published in the PNAS Journal, researchers investigated the impact of dietary flavanols on the cognitive aging component associated with hippocampal-dependent memory and the link ...