VVD-214 targets Werner helicase (WRN), a synthetic lethal vulnerability in cancers with high microsatellite instability (MSI-high) or deficient mismatch repair (dMMR) Global Phase Ib clinical study ...
Abstract: This study comprehensively investigates and compares the electromagnetic force characteristics in external-rotor surface-mounted permanent magnet machines, considering the modulation effect.
IDE892 is a potential best-in-class MTA-Cooperative PRMT5 combination partner with MAT2A and pan-RAS inhibitors, with favorable drug-like properties IDE892 has a CYP3A4 IC50 greater than 45 micromolar ...
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