The American College of Cardiology (ACC), the American Heart Association and nine other leading medical associations, today issued an updated guideline for the management of dyslipidemia—abnormal ...

Enlicitide decanoate, an oral proprotein convertase subtilisin–kexin type 9 (PCSK9) inhibitor, was shown to reduce low-density lipoprotein (LDL) cholesterol levels in a phase 2 trial; longer-term data ...

Every cell in the human body is surrounded by a semi-permeable membrane that needs to protect the contents of the cell while also allowing essential nutrients and ions to pass through. Compounds ...

Cell membranes cradle, protect, and gatekeep living cells. Membranes can even affect how a cell behaves. But membranes' own erratic behavior has puzzled scientists for years. Turns out, it's all about ...

The lipid asymmetry of the plasma membrane and its regulated release through lipid scrambling are critical determinants of membrane properties and functions. Such scrambling occurs during many ...

Metabolic dysfunction–associated steatohepatitis (MASH) is a progressive liver disease linked to fibrosis. The role of specific lipid species in its pathogenesis remains debated. Using dietary, ...

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

New study demonstrates that one type of lipid is so critical for immune evasion that certain cancers cannot proliferate without them. Modulating intake of dietary lipids could open up an avenue for ...

Scientists have found that 93% of the lipids in brain tissue are distributed differently in the white and gray matter, the subcortex, the visual and motor cortices, and the prefrontal cortex, which is ...

We conducted nested case–control studies of CHD among 3438 individuals (1719 pairs), including 1084 White Americans (542 pairs), 1244 Black Americans (622 pairs), and 1110 Chinese adults (555 pairs).