New platform gives researchers access to the quantity and quality of antibody-antigen affinity and structural data required for next-generation protein engineering models. Atlas by the Numbers Atlas ...
Structural biology has long been a leader in open data culture; the Protein Data Bank (PDB), Electron Microscopy Data Bank (EMDB), and Biological Magnetic ...
9don MSN
Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation
The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...
The AI-based program AlphaFold predicts a protein’s 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...
The newly developed experiment-guided AlphaFold technology (green) can predict protein structures across a wider conformational space than the existing AlphaFold3 (red). Provided by Maddipatla et ...
A peptide vaccine targeting PCSK9 has demonstrated sustained antibody responses and reductions in LDL cholesterol and atherosclerotic plaque formation in animal models, offering a potential long-term ...
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of death worldwide. Elevated low-density lipoprotein cholesterol (LDL-C) is a ...
Sam Eckholm on MSN
Watch a 70-ton US battle tank fire at a target over a mile away
The video goes inside the M1 Abrams, a 70-ton U.S. Army battle tank built around speed, armor, and a 120-millimeter cannon.
Anthropic's Claude Science is an AI workbench that unifies a scientist's tools and lets agents run the analysis, with a reviewer agent to check it.
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