The flow of ions through cation-selective members of the pentameric ligand-gated ion channel family is inhibited by a structurally diverse class of molecules that bind to the transmembrane pore in the ...
Through a structural and functional approach, researchers from the Icahn School of Medicine at Mount Sinai and Stanford University Medical Center identified physical binding sites for cholesterol in ...
Most ion channels are very selective about the ions that may or may not pass through them. They may be conductive for potassium ions and non-conductive for sodium ions, or vice versa. However, a ...
Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai, New ...
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