Many cancer-associated mutational signatures remain unexplained. Team CAUSE aims to connect DNA damage, mutational patterns, ...

As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...

Synthetic cell SpudCell, the first built from non-living components by University of Minnesota synthetic biologists Kate ...

A tiny bubble of lipids, enzymes and DNA has done something biologists have chased for years: it carried out a full cycle of ...

Scientists from the University of Minnesota say they have created the first-ever synthetic cell built entirely from scratch, ...

Scientists built a synthetic cell that combines more lifelike properties than ever before — proof of concept that it’s possible to bring nonliving materials to life, or something close to it, in the ...

Every time a cell copies its DNA, parts of the genome are exposed and vulnerable to damage or errors. Molecular biologist ...

Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("Acurx" or the "Company") is a late-stage biopharmaceutical company developing a new class of small molecule antibiotics for difficult-to-treat bacterial ...

Viruses play a major role in the functioning of ecosystems. They profoundly influence the dynamics of microbial communities, flow of matter and global biogeochemical cycles. Yet despite their ...

Definition: A microarray is a small, flat substrate carrying an ordered grid of microscopic probe features, each containing a known biological molecule, that is used to measure many molecular targets ...

There are photosynthetic bacteria known as cyanobacteria, and these microbes helped generate the oxygen that paved the way for complex life to survive on Earth. Researchers have now found that these ...

Alphaherpesviruses hijack host epigenetic regulation by promoting HDAC1/2 nuclear export and degradation to activate the DNA damage response, revealing new antiviral therapeutic targets.