During B and T lymphocyte development, antigen receptor diversity arises through V(D)J recombination, a process driven by the RAG1/2 endonuclease that introduces programmed double-stranded DNA breaks ...

Lymphocyte development relies on the deliberate induction and precise repair of DNA double-strand breaks (DSBs) to generate the diverse repertoire of antigen receptors that underpin adaptive immunity.

Effect of BL-8040, high-affinity CXCR4 antagonist, on T-cell infiltration, tumor growth, and synergy with immunomodulatory agents. This is an ASCO Meeting Abstract from the 2017 ASCO Annual Meeting I.

Atypical lymphocytes are types of white blood cells that a person’s immune system produces. They help fight infections and diseases. High levels of atypical lymphocytes may indicate health issues.