May 18, 2025 · Prednisone is currently recommended as the first-line treatment for pulmonary sarcoidosis but is associated with many side effects. Methotrexate, which is recommended as …

A problematic pattern of opioid use leading to clinically significant impairment or distress, as manifested by at least two of the following, occurring within a 12-month period.

Sep 25, 2024 · Tulisokibart is a tumor necrosis factor–like cytokine 1A (TL1A) monoclonal antibody in development for the treatment of moderately to severely active ulcerative colitis. A …

May 14, 2025 · Narcolepsy type 1 is a disorder of hypersomnolence caused by a loss of orexin neurons, which results in low orexin levels in the brain. In this phase 2, randomized, placebo …

Mar 6, 2024 · No treatment has surpassed platinum-based chemotherapy in improving overall survival in patients with previously untreated locally advanced or metastatic urothelial …

Discover research and guidelines published by NEJM Clinician related to Stroke (Neurology/Neurosurgery).

Jun 21, 2023 · Lateral epicondylitis typically resolves without treatment in 6 to 12 months. No strong evidence has shown long-term benefit with any treatment. Glucocorticoids can provide …

Idiopathic intracranial hypertension, also called pseudotumor cerebri, refers to elevated cerebrospinal fluid (CSF) pressure that develops most often in women of reproductive age with …

IT has now been well established that the leukocyte alkaline phosphatase in chronic granulocytic leukemia is very low, whereas in morphologically similar cell populations of polycythemia rubra …

Jul 8, 2010 · Carotid-artery stenting and carotid endarterectomy are both options for treating carotid-artery stenosis, an important cause of stroke. We randomly assigned patients with …