When should factorial designs be used for late-phase randomised controlled trials
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When should factorial designs be used for late-phase randomised controlled trials
Presentation by Ian White (MRC Clinical Trials Unit at UCL) on 7 October 2025 Factorial designs often require fewer resources and participants than alternative designs, but they are not widely used. We identified clinical, practical, statistical and external aspects that make factorial designs more desirable. An overarching aspect is that a ...
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